Apolipoprotein E4 polymorphism as risk factor for coronary heart disease among Indian subjects
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چکیده
منابع مشابه
Evaluation of Apolipoprotein A5 Polymorphism in Coronary- Heart Disease Patients
Background and Objectives: Apolipoprotein A5 (APOA5) gene is important in determining plasma triglyceride levels, a major cardiovascular disease risk factor. Mutation in this gene affected plasma triglyceride level. We looked for possible associations of the APOA5 gene polymorphism S19W with coronary heart disease (CHD) in a sample of Iranian population. Materials and Methods: A total of 7...
متن کاملApolipoprotein E polymorphism and coronary heart disease.
Apolipoprotein E is a constituent of various lipoproteins and plays an important role in the transport of cholesterol and other lipids among cells of various tissues. The gene is polymorphic with three alleles (epsilon2, epsilon3, and epsilon4) coding for isoforms E2, E3, and E4 and having different binding affinities for the apo E receptors. While the epsilon2 allele is associated with elevate...
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background: coronary artery disease is recognized as one of the three major causes of mortality around the world. the role of inflammation in producing coronary artery disease has been established in previous studies. since periodontitis, which is highly prevalent, is considered as a cause of inflammation, its influence on producing coronary artery disease was investigated in the present study ...
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BACKGROUND Overweight is associated with an increased cardiovascular risk which is only partially explained by conventional risk factors. The objective of this study was to evaluate lipoprotein(a) [Lp(a)] plasma levels and apolipoprotein(a) [apo(a)] phenotypes in relation to coronary heart disease (CHD) in overweight subjects. METHODS A total of 275 overweight (BMI > or = 27 kg/m2) subjects, ...
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BACKGROUND Homocysteine (Hcy) is an intermediate formed during the catabolism of sulphur containing essential amino acid, methionine and Less than one percent of tHcy is found as the free form. Development of atherosclerotic changes and thrombo-embolism are common features in patients with homocysteinuria. This study was conducted to assess the relationship of Hcy and coronary heart disease (CH...
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ژورنال
عنوان ژورنال: Indian Journal of Clinical Biochemistry
سال: 2002
ISSN: 0970-1915,0974-0422
DOI: 10.1007/bf02867947